• Zoeken
« Terug naar home

Evaluation of eHealth applications

eHealth use is on the rise, but issues with eHealth evaluations has been noted due to the difficulties of creating controlled eHealth experiments. Recently, Kelly, Jenkinson, and Ziebland (2013) reported the development of a questionnaire to measure the impact of eHealth on its users. Through secondary data analysis of narrative interviews relating to internet use regarding health information among patient and carers, five themes relating to the impact of eHealth were identified: (i) use of eHealth to gather information, (ii) use of eHealth to feel supported, (iii) use of eHealth to connect with other patients/carers, (iv) use of eHealth to consult where to access appropriate health services, and (v) use of eHealth to affect health behaviors.

After consulting focus groups and comment forms of lay persons using local health care services to confirm these five themes, statements from the narrative interview transcripts were selected to form 67 items (e.g. “The internet is a reliable resource to help me understand what a doctor tells me”), covering the five themes. These items were refined by consulting experts and patients. Following this refinement two pools of items were selected: the first pool (23 items) related to general attitudes towards eHealth, and the second pool (39 items) related to attitudes toward a specific eHealth tool. The final questionnaire, the eHealth Impact Questionnaire (eHIQ) consists of two parts consistent with these pools, the first part consists of 11 items, while the second part consists of 33 items.

The current project sets out to translate the eHealth Impact Questionnaire to Dutch, and testing its psychometric properties in the Dutch population of eHealth users.

The eHIQ was translated in accordance to the COSMIN criteria. The questionnaire was first forward translated from English to Dutch by two translators, one being an eHealth expert and one being a language expert fluent in English and with Dutch as his mother tongue. These two translations were combined into one Dutch questionnaire by two independent reviewers. In the case of discrepancies between the two independent reviewers, the translation was discussed until consensus was reached.

The translated questionnaire was back translated to English by two language experts fluent in Dutch and with English as their mother tongue. The back translated questionnaire was compared to the original questionnaire two independent reviewers. Discrepancies between the back translation and original questionnaire were discussed. Adjustments to the Dutch questionnaire were made when deemed necessary to reach wording that more accurately represented the English questionnaire.

The translated eHIQ, and some additional questions to test convergent validity, will be presented twice electronically to participants. The second presentation will be two weeks after the first to investigate test-retest reliability.

The COSMIN criteria will be followed for validity and reliability analyses. Construct validity will be tested by confirmatory factor analysis for which five factors, one for each domain used in the creation of the eHIQ, are assumed. Convergent validity will be assessed through correlating the eHIQ with the additional questions. Split-half reliability will be estimated using Cronbach’s Alpha, Guttman’s Lambda 4, and Guttman’s Lambda 6. Cronbach’s Alpha estimates the lower limit of split-half reliability, Guttman’s Lambda 4 estimates the upper limit of split-half reliability, and Guttman’s Lambda 6 estimates the average split-half reliability. Test-retest reliability will be estimated using Cohen’s Kappa of the two test sessions. The measurement error will also be estimated between the two test sessions. To test internal validity of the questionnaire, it will be analyzed using the IRT Graded Response Model, as it models Likert scales exceptionally well.

This project is financed through the Citrienfund via the eHealth programme of the Dutch Federation of UMC's (NFU).

For questions, please contact:

K. Neijenhuijs, MSc (research), Behavioural Scientist

E-mail: k.i.neijenhuijs@vu.nl

prof dr IM Verdonck-de Leeuw

E-mail:  s.biemans@vumc.nl

naar boven ↑

News flashes


PhD thesis Joeri Kalter

September 28, 2018 Joeri Kalter defended his thesis “Exercise and psychosocial interventions to improve quality of life in patients with cancer”. 


PhD thesis Sanne Duman-Lubberding

July 4, 2018 Sanne Duman-Lubberding defended her thesis "Online Patient Reported Outcome Measures to faciltate supportive care in Head and Neck Cancer patients".


PhD thesis Femke Jansen

January 15, 2018  Femke Jansen defended her thesis “Supportive care in head and neck cancer patients. Patient-reported needs and costs”. 

PhD thesis Janneke Rood

September 11, 2017 Janneke Rood defended her thesis "Perceived need for information and treatment decision-making in patients with hematological malignancies: not "one size fits all".


Amsterdam Public Health project

Within the context of the alliance VUmc-AMC Prof dr Ellen Laan (AMC) and prof dr Irma Verdonck-de Leeuw (VUmc) received a grant for the project "Sexual well-being in head and neck cancer patients".


Treatment of psychological distress in patients with head and neck or lung cancer cost-effective.
A recent study of PhD-student Femke Jansen and colleagues, recently published in the Journal of Clinical Oncology


PhD thesis Nadine Köhle

December 15, 2016 Nadine Köhle defended her PhD thesis "Hold on, for each other. Supporting partners of cancer patients via eHealth and positive psychology". 


PhD thesis Anne-Marie Krebber

December 2, 2016 Anne-Marie Krebber defended her PhD thesis "Stepped care targeting psychological distress in head and neck cancer and lung cancer patients".


PhD thesis Nadia van der Spek

September 7, 2016, Nadia van der Spek defended her PhD thesis "Meaning-centered group psychotherapy for cancer survivors: development, efficacy, and cost-utility". 


EORTC QLG Newsletter Spring 2016
The EORTC QLG  Spring Meeting took place on April 20th and 21th 2016 in Oslo. The Spring newsletter of the EORTC QLG is now available. 

PhD thesis Ingrid Cnossen

April 12, 2016, Ingrid Cnossen defended her PhD thesis entiteld “Self-management Supporting Rehabilitation in Head and Neck Cancer Patients”. 


VU/VUmc and Red-kite sign agreement for the provision of the Oncokompas in healthcare.

The VU University Amsterdam and VUmc Cancer Center Amsterdam work with Red-kite, distributor of software for hospitals in Netherlands. (November 3, 2015)


PhD thesis Christine van Gogh

December 4, 2015, Christine van Gogh defended her PhD thesis entiteld “Functional outcome of early glottic cancer”. 

Book presentation

On June 15th, 2015, Irma Verdonck presented the book "In Tune Without Cords" (in Dutch: VerderZonderStembanden) to Rob Burdorf, the president of the patient society for patients after laryngectomy.


PhD thesis Florien Boele

May 11 Florien Boele defended her PhD thesis, entitled "Towards improving health-related quality of life in glioma patients and their informal caregvers".


PhD thesis Trille Kristina Kjaer

May 8, Trille Kjaer will defend her PhD thesis entitled "Late effects after treatment of head and neck cancer and use of patient reported outcomes in clinical practice." Irma Verdonck is member of the committee.


Niels Stensen Fellowship
Florien Boele has received a Niels Stensen Fellowship. This is a scholarship that is awarded annually to a number of outstanding researchers who have recently obtained their PhD degree, to gain working experience abroad. Florien Boele will go to Pittsburgh (United States) and Edinburgh (Scotland) in 2015 and 2016.

Key paper

The publication “Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments” of A.M.H. Krebber et.al is chosen by the Editors as one of the key papers in Psycho-oncology, (issue June 2014).


On April 10th, 2014, the first edition of the Value Based Healthcare Prize took place. The prize for the most exceptional initiative in collaborations went to Jippa, a collaborative by VUmc, CZ, Radboud UMC and Tilburg University.


In November 2013 the NVPO organised the International Congress "Innovation in Psycho-Oncology". The researchgroup held several presentations and posters.


Interested in oncological care chain? Come 2 October 2013 to the 3rd MuON symposium in hospital Gelderse Vallei. Keynote speaker Michel van Schaik (Director Rabobank) about Innovation in the care!


12 april 2013: KWF Kankerbestrijding / Alpe d’HuZes has granted the research proposal Netherlands Quality of life and Biomedical Cohort Studies in Cancer (NET-QUBIC).

Marieke de Bruijn will defend her PhD thesis on 10 juni 2013 at 15.45 pm.

Support our bicycle team for Alpe d'HuZes 2013!

On 6 June 2013 our team living together with cancer will cycle the Alpe d'HuZes! This in the fight against cancer. At this moment there is already more than 1500 euro donated. Do you support us too?


The 15th World Congress of Psycho-Oncology and Psychosocial Academy will be held in Rotterdam, 4-8 November 2013. www.ipos-society.org/ipos2013/.


29 January 2013. Pink Ribbon has granted a project to develop and evaluate an online training for cancer patients with insomnia (Annemieke van Straten), and a project to develop and evaluate a breast cancer module for the OncoKompas (Nelly van Uden).


Charity Symposium "Living with cancer"

On December 19, 2012 there will be a Symposium ''Living with Cancer''. This is a charity symposium on meaning centered psychotherapy for cancer patients. Read more about it at the tab News at the left.


15 November 2012: Hoe?Zo! Radio interview with Irma Verdonck on stress and cancer.


October 2012: Interview with Irma Verdonck in Psychologie Magazine.


September 9, 2012. Interview Hans van Willigenburg with Irma Verdonck on Radio 5.


August 2012. Five students finish their MSc thesis and graduate as MSc in Clinical PSychology.


June 28-30, 2012: International symposium on Supportive Care in Cancer (MASCC ISOO) at New York. Kevin Yap and Irma Verdonck organise a workshop on e-health and supportive care.


Record for Alpe d'HuZes 2012. The sponsor action Alpe d'HuZes (6 and 7 June) 2012 has already yielded the record amount of 28.5 million euros.


June 6-8, 2012: Our research group contributes to Alpe d'HuZes as volunteers.


April 20, 2012: Nelly van Uden will give a presentation about OncoKompas at a conference about  ICT in health care in Barcelona.


March 16, 2012: NVPO congress in Utrecht, we contribute with 2 oral and 2 poster presentations and a workshop.


January 1, 2012: The project POLARIS project has officially started.


December 22, 2011: Radio program DeGids.fm, Felix Meurders interviews Corien Eeltink on sexuality and cancer. 


November 2, 2011: KWF / Alpe d'HuZes funds a grant for the development and evaluation of an online intervention for informal caregivers of cancer patients.


October 30, 2011 In the national television program "Gesprek op 2", Daphne Bunskoek interviewed Irma Verdonck on living with cancer.


October 28, 2011: www.oncokompas.nl is online!


October 23, 2011: Alpe d'HuZes hands over more than 20 million euros to the Dutch Cancer Society!



Team work

Our research projects are embedded in the two largest research institutes of VU University in Amsterdam: VUmc CCA-VICI (Cancer Center Amsterdam) www.vumc.nl/afdelingen/CCA-V-ICI/ and EMGO+ (Institute for Health and Care Research emgo.nl

We work closely with patients and their caregivers and with researchers and physicians at VU University and VU University Medical Center in Amsterdam and other research institutes and hospitals in the Netherlands and worldwide. Team work is crucial  improving research and translating results into clinical practice.

© Copyright 2011 - Samen leven met kanker - Alle rechten voorbehouden | Disclaimer